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Strep and pediatric acute-onset neuropsychiatric syndrome, or PANS

  • Writer: ehsmileninjas
    ehsmileninjas
  • Apr 28, 2017
  • 1 min read

This months issue of Discovery Magazine there was an interesting article on PANS (Peditric acute-onset neuropsychiatric syndrome) and the dangers of Streptococcus pyogenes bacteria (can cause strep throat — and worse).

Scientists have seen the connection between infections and some cases of neuropsychiatric diseases. Syphilis was a major contributing factor of dementia and was frequent among the insane prior to the discovery that antibiotics would cure it. There is mounting evidence of Bartonella, the microbial cause of common cat scratch fever, sometimes inducing anxiety, rage and psychosis. These diseases are caused by living organisms active within the brain itself. If you can exterminate the living organisms early enough and all symptoms will subside.

That can be difficult when it takes as little as five days for strep to produce autoantibodies that can damage heart tissue, and can lead to rheumatic fever. Sydenham chorea was like rheumatic fever of the brain, thought to occur when rheumatic fever progresses and strep (emboldened by fever) breaches the blood-brain barrier (BBB), the tight wall of endothelial cells ordinarily there to protect the brain from the outside world. Once they break into the brain, the autoantibodies attack the basal ganglia, causing the afflicted to jerk and writhe in a manner resembling the worst cases of the tic syndrome Tourette’s. OCD (obsessive Compulsive Disorder) is thought to have a strong connection to Strep.

Alison Mackey/Discover. Brain: Alila Medical Media/Shutterstock. Olfactory close-up: Designusa/Shutterstock

Alison Mackey/Discover. Lymphatic System: Adapted from University of Virginia Health System

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